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01x07 - Psychedelics

Episode transcripts for the TV show, "History by the Numbers". Aired: March 22, 2022.*
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This series is loaded with mind-blowing factoids and stats, entertaining expert interviews, and infographics injected with cheeky humor.

01x07 - Psychedelics

Post by bunniefuu »

- I have done psychedelics,

less now, but once a lot.

- Yeah, I have exactly zero

experience using psychedelics.

- Reality is distorted somewhat,

and there's a lot of laughing.

- [Narrator] Psychedelic

drugs have impacted humanity

for as long as

there've been people

who wanna get their minds blown.

- There has been

hardly any society

that hasn't used some kind

of psychoactive substance.

- It's been used

ritualistically,

it has been used

therapeutically.

- [Narrator] They can cause

shifts and perspectives

that can be terrifying

or revolutionary.

- I definitely think

psychedelics played a role

in changing the status quo.

- Women went from the

kitchen to the boardroom,

people of color from the

woodshed to the White House.

g*y people from the

closet to the altar.

The one ingredient in the

recipe is social transformation

and change is that millions

of us laid prostrate

before the gates of awe,

having taken a psychedelic.

- [Narrator] These

substances are so powerful

that the tiniest amount

can make a big difference.

- Two hundred and

fifty micrograms.

- Two hundred and fifty.

- Like, let's say you

take 350 micrograms,

then what happens?

- Two hundred and fifty.

- Two hundred and

fifty micrograms,

that's gonna change everything.

- [Narrator] Such a

tiny amount can change

not only the way

we see the world,

but change the world itself.

This is a psychedelic history

with trippy numbers

that are groovy, man.

(upbeat music)

Let's begin at the beginning

and start with the number one.

Psychedelics like

magic mushrooms and LSD

are a class of drugs that

alter the user's cautiousness

They can cause hallucinations

and ecstatic feelings

of communion.

- Psychedelics are popular now

because they help us have

experiences and thoughts

beyond what is considered

common or normally acceptable.

And people often really

enjoy those experiences.

- [Narrator] Or they can cause

fear, paranoia and confusion.

- Bad trips are really bad.

The hallucinations takeover,

paranoia sets in,

and a person dissolves

into the experience and

are essentially assaulted

by the images, sounds

and hallucinations.

- [Narrator] Which is why,

according to the U S

Drug Enforcement Agency,

psychedelics are a

controlled substance

and a schedule 1 drug.

But if you're not a

government agency,

being number one is

sometimes the whole point.

Take Steve jobs.

- Steve Jobs is the entrepreneur

and co-founder of

Apple computer.

Before that, he was a hippie.

- We started Apple because we

wanted the product ourselves.

- [Narrator] Job said

that using psychedelics

was a profound and positive

life changing experience.

- But I don't think it's

because of the experience

of LSD that Jobs was creative,

but I think happened was

that people like Jobs,

rewrote the meaning

of computers,

turned them from tools

of cold w*r industry,

into tools of

personal exploration.

- [Narrator] At the same time,

turning Apple into the number

one company in the world.

- A lot of people that I

know doing psychedelics

are not inventing

any iPhones or iPads.

- The iPhone is the ultimate

toy for somebody who's high.

- Drug use is

fantastic for ideation.

It's not great for

actually working on things

and implementing them

being functional.

- [Narrator] Admittedly, Steve

jobs was one in a million

or perhaps one in 32 million.

Ten percent of the adult

population in the United States

has used psychedelic

drugs at least once.

That's 32 million people.

It's a psychedelic Renaissance.

And surprisingly, it

puts the 1960s to shame.

Today's millennial might not

look like yesterday's hippie,

but if you're in your thirties,

you are 10 times more

likely to use psychedelics

than the flower

power generation was.

- [Comical voice] Groovy.

- [Narrator] LSD,

the psychedelic of

the hippie generation

was discovered as a

result of 25 trials

and one tiny error.

It's 1943 in Basel, Switzerland.

Albert Hoffman is

doing medical research.

- [Comical voice]

Ah, very interesting.

- [Narrator] And he is just

about to accidentally kick off

the modern psychedelic era.

- Hoffman from a young age

was a mental explorer.

He was very spiritual.

His friends were surprised

when he decided to

become a chemist.

- Nineteen forty three,

working on ergot,

this curious fungal parasite,

Hoffman had made on a whim,

the 25th of a series

of indole alkaloids

when suddenly he got dizzy.

- [Narrator] A tiny trace has

found its way onto his skin.

As little as 20

millionths of a gram.

- As he put it, he felt quite

sick, but not unpleasantly.

- [Narrator] Hoffman

scientific curiosity

is aroused by this

one tiny mistake.

And on April 19th, he

ingests a higher dose,

250 micrograms,

then decides to head home.

- He was riding his

bike back at home

and he end up going

on the most momentous

bicycle ride in history

Because the

substance was LCD-25.

He went on the world's

first acid trip.

- Can you imagine riding home

on your bicycle hallucinating,

seeing, you know, purple

rings around the lights,

seeing the traffic going by

and making strange

cenesthetic sounds.

Tsh, tsh, tsh, tsh, tsh, tsh.

I don't know whether it

would've been terrifying,

delightful or both.

- He was watching

the road one minute.

And then the next second,

the whole thing turns into

an episode of the Simpsons.

- If I'm tripping ba*ls,

I don't want to be operating

any sort of a vehicle.

I can't even

operate this vehicle

by putting one foot

in front of the other.

- You made it home safe,

that's all that mattered.

- [Narrator] This

is an electrifying

experience for Hoffman

who believes he has

discovered a sacred drug,

a drug so powerful that

this magic bike ride

is fueled by an absolutely

teeny weeny dose.

- Two hundred and

fifty micrograms

is 10 times lighter

than a human hair.

- Two hundred and

fifty micrograms

is a pretty small amount,

but it can have

a massive impact.

Neuro-transmitters are already

relatively small molecules.

So it wouldn't take a

whole lot of lysergic acid

to completely reorient

the way you see the world.

- [Narrator] So what exactly

does this minuscule dose

do to Hoffman on his

famous bike ride?

- Shuts down parts of

your prefrontal cortex.

So there was parts of yourself

that associate your identity

with how you look,

how you dress,

what you're capable of.

All those regions go off-line.

You're no longer

so associated with

your identity,

that you can only see your

existence through your lens

at that time.

- [Narrator] Hoffman presents

his LSD findings to Sandoz,

the pharmaceutical

firm he's working for.

But they consider it of no

practical use and shelve it.

Ten years later,

Hoffman's moldering joy

drug will be dusted off

by the unlikeliest of customers.

It's the 1950s an agricultural

scientist, Sidney Gottlieb,

is living in a rural cabin

without any running water

when he's recruited by the CIA

in the fight against communism.

- We're trying to

invent faster than them,

we're trying to invent more

destructive devices than them.

We're trying to

impact, politically,

more countries than they are.

So it's literally a two-country

fight for world domination.

- We're locked in a cold w*r

and American state

officials were terrified

that there were these

secret communist forces

slipping into our society.

- Do you have any evidence

of any claim to win the case

if there's any subversive

amongst these young men.

(b*mb exploding)

- [Narrator] The U

S has a stockpile

of around 1,000

nuclear warheads,

but that's not nearly

enough weapons for the CIA,

which wants a

thousand times more.

And Gottlieb is the

man to get them.

- [Woman narrator] The

CIA taps him to come in

and research potential

poisons for warfare uses

and Gottlieb ends up

getting the nickname,

the black sorcerer.

- [Comical Voice] The

sorcerers' on the case.

- [Narrator]

Gottlieb thinks way,

way outside the box.

Later in his career,

he will try to take

down Fidel Castro.

- [Comical voice]

Viva la Revolution.

- [Narrator] And he's not

above using slapstick comedy

to do it.

- [Comical voice] Ouch.

- [Narrator] He

attempts to k*ll Castro

with a poisonous cigar,

and exploding conch shell,

and a pair of radioactive shoes

designed to make Fidel

Castro's beard dropout.

- The U S was really desperate

to find any kind of weapon

that would allow them

to one up the Russians,

whether that's a warhead

or some sort of chemical weapon.

- [Narrator] When

Gottlieb hears about LSD

from an operative

in Switzerland.

- [Comical voice] Hello.

- [Narrator] He spies a one

in a million opportunity.

- The CIA, one of the

things they were looking for

was some sort of truth serum,

and they were hoping that

LSD would provide that.

- [Narrator] Gottlieb

wants to corner the market

before the Soviets can get

to this powerful new drug.

So he agrees to pay $240,000

for what he believes is

the world's entire supply,

100 million doses.

He not only keeps the drug out

of the hands of the Russians,

but he also becomes

the unwitting drug mule

who brings LSD to the states.

- There were already rumors

of Chinese mind control

being experimented

on American soldiers

during the Korean w*r.

- [w*r Narrator] Then there've

been talk of brainwashing.

wasn't brainwashing a big

thing with the Chinese?

- [Narrator] In 1953,

the CIA appoints Gottlieb

as head of project MK-Ultra,

a program that will

test drugs like LSD

on unsuspecting members

of the American public.

Gottlieb will head

MK-Ultra for 20 years.

- [Comical voice]

That's a long time.

- [Narrator] In that time,

he will oversee 149 mind

control experiments,

more than 25 of

these experiments

involve administering LSD

to thousands of

non-consenting victims.

One test subject was given

LSD for 174 consecutive days.

But much of MK-Ultra's research

is carried out in

broad daylight.

- The subjects of MK-Ultra

with which I'm most familiar,

were college students

and young people

here in Northern California

administered as a

standard drug trial,

just as any other drug

trial would have been.

- [Narrator] For all

the time and effort,

the extensive

MK-Ultra experiments

failed to produce any

practical applications.

- I really don't think LSD

would make a great truth serum.

You're still capable

of lying on acid.

- They gave acid

to Ted Kaczynski,

a brilliant mathematics

student at Harvard,

and then subjected him to

a traumatic experience.

Guess what gave the

world the Unabomber?

It's like, that's

so inconsiderate.

- I don't know what type of

truth you're going to get.

It might be somebody's own

truth, which is I am a tree.

- I don't think LSD worked

as a truth serum at all.

I don't see any

evidence for that.

I think more recently,

LSD has been shown to offer

a sense of interconnection.

With MK-Ultra was not

looking to help people

feel more peaceful and

happy with one another.

MK-Ultra was looking

to stave off communism.

- [Narrator] The CIA's truth

serum has zero success,

but it will prove to

be a game changer.

Thanks to 14 tie dye t-shirts.

The CIA's MK-Ultra program had

some unintended consequences.

They were trying to root out

subversive elements in America.

But for many of the

participants of the experiments,

LSD opened their eyes to a

new way of seeing the world.

The CIA gave the gift

of LSD to the 1960s,

creating a whole new class

of subversive weirdos,

beat poet, Allen Ginsburg,

and Grateful Dead

lyricist, Robert Hunter,

had their first experiences

with LSD in these experiments.

- This is a program designed

to produce the truth serum,

but it ends up energizing

the counter-culture.

- [Narrator] In the late 1950s,

Ken Kesey is a young writer

who was working in

a psychiatric ward

and volunteering in drug trials

to make some extra money.

- Ken Kesey was in

the process of writing

One Flew Over the Cuckoo's Nest

and he participated in the

MK-Ultra studies in 1959.

He said he suddenly cracked open

and became a different

kind of person.

- [Narrator] He formed a group

of 14 psychedelic adventurers

called the Merry Pranksters.

And fits them out with a

vehicle designed to travel

into the cosmic

heart of America.

- Imagine if you would,

the same school bus to

pick you up everyday

as you went to school,

covered in swirling pinks

and greens and yellows.

- [Narrator] On the front,

they paint their destination.

- [Comical voice] Further.

- [Narrator] This becomes

the name of the bus,

as well as the mission statement

for the Merry Pranksters.

- They become kind of

1960s Instagram influencers

going around and putting

on artistic shows,

sharing LSD with people

and living #vanlife.

The kind of free

artists lifestyle

that is very aspirational today.

- [Narrator] They drive

from California to New York,

a 12-day hallucinogenic odyssey.

When the bus swerves off an

Arizona highway into a swamp,

they pour paint into the

water and dip their clothes,

inventing the classic

uniform of the 1960s.

- [Comical voice]

Love the colors.

- [Narrator] The

tie dye t-shirts.

And whether antics attract

the attention to the police.

- [Comical voice]

Groovy ticket, baby.

- [Narrator] They skate

away without consequences

because in 1964, LSD is

still completely legal.

The Merry Pranksters

create the template

for the hippie movement,

freedom, spontaneity,

and communion with

art and nature.

It's all an alternate universe

that's unlocked with LSD.

A substance that is still legal,

but finding a source

for the stuff is tricky.

- Owsley Stanley or Bear

was famous for being the

live mixing board operator

for the Grateful Dead,

but he was also the

one that made the LSD

that was given to dozens of

musicians from the time period

that we associate

with psychedelics.

- [Narrator] Between

1965 and 1967,

Owsley Stanley produces

500 grams of LSD,

more than 5 million doses.

He produces so much, in fact,

that Owsley is added to the

Oxford English dictionary,

meaning an extremely potent

high quality form of LSD.

But the sixties will be a

decade split down the middle

by the number 23.

Owsley calls his

acid, white lightning,

and Ken Kesey and the pranksters

begin to distribute it

at a series of 23 parties

they call, acid tests,

multimedia events

that celebrate LSD.

- You would've have

seen flickering lights.

You would have heard the

music of the Grateful Dead.

You would've seen DayGlo paint.

There's just an

enormous dance party

and people are tripping

and they are forming

a new kind of society

connected by the sensation

of shared consciousness.

- [Narrator] Tales

of Kesey's acid tests

spread like wildfire.

LSD becomes a rite of passage

for the baby boom generation.

But the party suddenly

stops on May 30th, 1966.

Enter Donald L Grunsky,

Senator for California's

23rd district,

whose bill will make LSD

ill*gal in the state.

- [Comical voice]

Uh, bummer, man.

- [Narrator] But the genie

isn't going back in the bottle.

Legal or not, LSD is

part of a cultural shift

that's sweeping America,

a shift that's defined

by six simple words.

It's January 14th, 1967,

Timothy Leary is a 47

year old psychologist

who has been fired from

Harvard for his work on LSD.

And he's become a full-time

evangelist for the drug.

He is about to

address 25,000 hippies

who have gathered at San

Francisco's Golden Gate Park.

Many of them are naked.

- The Human Be-In was a

festival in Golden Gate Park.

People came from

all over the city.

They put flowers in their hair.

- [Narrator] A parachuter

throws free doses of LSD

to the crowd.

The local chapter

of the Hells Angels,

mellowed by LSD,

are the security.

- They listened to

music by Janis Joplin

and Jefferson Airplane.

They hear Alan Ginsburg

chanting Hare Krishna.

- [Narrator] The hippies

are confronting the darkness

in their country with love.

- [Comical voice]

Make love not w*r.

- This is during

the Vietnam w*r.

This is in the

wake of race riots

that are occurring

around the United States.

The Human Be-In

offers us a glimpse

of a different America,

an America that could be

based around peacefulness.

- [Narrator] Timothy

Leary takes the stage

and utters six words that

will define a generation.

- Turn on,

tune in,

drop out.

- Turn on, take LSD.

Tune in to the secret

system of vibrations

and currents that LSD revealed,

and drop out of mainstream

bureaucratic society.

They thought that if they did,

society as a whole would change,

we'd have a new America.

- You know, telling kids

to just tune in, turn out

and drop out, seems

pretty negative,

especially from a teacher.

Never encourage my

students to drop out.

- I'm going to pass on to my

psychedelic co-religionists

the lessons that we have

learned over the last six years.

- I think many young

people, even today,

connect to with the phrase,

turn on tune in and drop out,

because it suggests a

spiritual connection

between us and the

larger universe.

- [Narrator] The Human Be-In

was the dress rehearsal

for Woodstock,

a three-day music festival

in upstate New York.

That includes a tent to help

people navigating bad trips.

- Four hundred thousand people

showing up in the same place

to share an experience,

to receive a message and to

commune with one another.

- [Narrator] Well, what

the hippie generation

doesn't realize is that they're

late for their own party.

Approximately 9,000 years late.

In 1955, Gordon

Wasson is a banker,

but more importantly, he's a

mycophil, a mushroom lover.

And he'll be one of the

first Americans to discover

there was more than one

way of getting high,

more like 200 ways,

sprouting up all

over the planet.

But he wouldn't have found out

if it had not been

for the number 58.

- It's important

to remember that,

whereas the era of Timothy Leary

led to the complete

popularization of

these substances,

up until 1960,

those who studied these

plants were really remarkable

at collecting

handful of scholars.

- [Narrator] Gordon

Wasson has a theory

that there are cultures

who use mushrooms

for their religion.

- [Comical Voice] Hmm, I wonder?

- [Narrator] So when he

learns from a pen pal

that the people in

Oaxaca have a mushroom,

they call Teonanacatl,

God's flesh.

He gets there as fast as he can.

- The Mazatec people were

not the only indigenous group

that used psilocybin,

but he was the

one that he found.

- [Comical voice] Ola.

- [Narrator] Wasson meets

a woman named Maria Sabina,

who knows about Teonanacatl.

- Maria Sabina was a

traditional Mazatec healer.

In many ways she was just

one among other healers.

She was very humble,

poor local woman.

- [Narrator] Gordon

Wasson pretends to be sick

and persuades Maria

to let him attend

one of her all night Veladas

or healing ceremonies.

He is the first outsider

to ingest this mushroom

in a sacred context.

And he photographs it.

- He wrote it up

for life magazine,

an editor picked a snappy title,

Seeking the magic mushrooms.

Timothy Leary had

a subscription.

He made his own

beeline to Cuernavaca.

The psychedelic

gold rush was on.

- [Narrator] Suddenly

the whole world knows

that if you want

magic mushrooms,

Maria Sabina is

the woman to see.

- Maria Sabina got

to be really famous,

but she also experienced

the cruelties of that fame.

- [Narrator] Maria's village

is overrun with hippies,

scientists and all kinds of

scumbag who just wanna get high.

- [Comical voice]

Hey, you know where

I can score some shrooms?

- [Narrator] To the police,

she's a drug dealer.

- Her house was burnt,

there was a lot of tragic

episodes in her life.

- [Narrator] Maria's life is

shattered by the attention

from the outside world.

Wasson on the other hand,

had a terrific Mexican

adventure paid for,

as it turns out by the CIA

as MK-Ultra sub-project 58.

When he was done,

he sent samples of the mushrooms

to his pal, Albert Hoffman.

- [Comical voice] You see,

it's all connected, man.

- From that point forward,

Americans became

fascinated by mushrooms.

You don't have to synthesize

them in a laboratory,

like LSD or MBMA.

You can just go in

the field, pick them,

dry them, and eat them.

- [Narrator] No one knows

how many species of mushroom

there are.

Though it's estimated there

may be as many as 3.8 million.

Of these, more than 200

are psilocybin mushrooms.

Psilocybin is the magic

part of magic mushrooms.

The chemical that causes

psychedelic effects.

Psilocybin mushrooms grow

across six continents.

There aren't any

mushrooms on Antarctica.

Mexico is the global hotspot,

home to 53 species

of magic mushrooms.

- Do mushrooms count?

Oh, then I have been

high on psychedelics.

- I like shrooms more,

if we're going to be

talking about drugs.

It's like acid with a

seatbelt, so it's nice.

- We don't realize that

in order to find out

what you can eat,

that people literally

had to try things

and make people aware

that this is something

you want to stay away from.

Or Hey, this mushroom right

here, it's nourishing.

And it gives you an interesting

perspective on life.

- [Narrator] And as

we're discovering,

people have been getting an

interesting perspective on life

for the last 9,000 years.

- Probably our very

earliest evidence

that people were using mushrooms

for reasons other than a food

is from the site of Tassili

N'Ajjer in Algeria .

We have a depiction

of a humanoid figure

who has a bee or insects' face,

but they're also surrounded

by an aura of mushrooms,

which suggests to us

that this is about a

religious experience.

- [Narrator] People have

been finding different ways

to alter their minds

for a long, long time.

And it's not just mushrooms.

They've been using flowers,

cacti, vines, and even toads.

- Of the 120 or so

recognized hallucinogens,

several of which

are questionable.

Fully 90% of them are from

the American hemisphere.

- It turns out Albert

Hoffman and Gordon Wasson,

not to mention Sydney Gottlieb,

weren't discovering

anything new,

which begs the question.

Why did it take the

west so long to catch on

when psychedelics can be

found almost everywhere?

One answer can be found hiding

somewhere in the number 548.

For many cultures,

psychedelics aren't drugs,

they're religious or

ritual sacraments.

- The use of psychedelics,

particularly,

has been really influential

for indigenous peoples

across the Americas,

but not only in Americas,

all over the planet.

- Indigenous people have

used these substances

for thousands of years and

having no drug abuse problems.

How did they do it?

Well, first they recognize

the use of these substances,

a legitimate thing to do.

They use their plants

in natural form,

which is pharmacological safer,

and critically, they

envelop the user

in a protective cloak of ritual

that insulates him or her

from the sometimes

dazzling psychological

and psychic power

of these substances.

And so that's the

path we should follow,

the path of the shaman.

- [Narrator] Standing at

just half an inch high,

the Psilocybe mexicana

magic mushroom

packs a psychedelic punch.

By contrast the Amazonian

psychedelic vine,

Banisteriopsis caapi,

is 2,352 times bigger

at 98 feet long.

But as Explorer, Manuel

Villavicencio, finds out,

size doesn't matter.

It's all about how you brew it.

In the 1850s,

Manuel Villavicencio is

following the path of the shaman

across Ecuador and in

the remote Eastern part

of the country,

he becomes immersed in the

traditions of the Jivaro people.

- He studied the Jivaro,

the Jivaro were famous and

a little bit exoticized

for the practice of shrinking

heads and things like that.

- [Narrator] Manual

Villavicencio watches

as the Jivaro

shaman brews a drink

from the bark of a giant

vine boiled for 12 hours.

By firelight, the shaman drinks

and hands it to Villavicencio.

He takes a swig and

suddenly he's swimming

or is he flying and

tastic birds glide by

and speak to him.

- [Comical voice] Hey,

man, how's it going?

- [Narrator] And then

he plunges to earth

to be consumed by

unimaginable horrors.

Manuel Villavicencio

has taken Ayahuasca,

one of the most potent

hallucinogens on the planet.

- Ayahuasca is a very

traditional sacred

plant of the Amazon

that has been used by more

than 17 indigenous groups.

Ayahuasca, it means

vine of the soul.

- The people of the

actual Northwest Amazon

say you're sucking at the

breast of Jaguar woman

when she tears you from her tit

and throws you in

the pit of vipers.

It's about getting

to the other side.

- [Narrator] Villavicencio

writes one of the first accounts

of Ayahuasca in his book,

Geografia Republica Del Ecuador.

- It was only

published in Spanish.

So it didn't get a

lot of visibility.

- [Narrator] It's one of the

most powerful psychedelics

known to humankind.

But Villavicencio's

obscured geography textbook

is no bestseller.

And the secret of

Ayahuasca will lie hidden

somewhere inside it's 548

pages for a hundred years.

But if Ayahuasca was one of

the best kept psychedelic

secrets of the last

century, it isn't anymore.

- Today, living in the bay area,

the Uber driver knows

about Ayahuasca,

the person who grow food

knows about Ayahuasca.

- [Narrator] But for

rookie Westerners,

this is not a substance that

should be taken lightly.

- The few people that I

know who've tried Ayahuasca

describe it as

physically really rough.

It makes you very

nauseously vomit.

- [Comical voice] Blaargh.

- Traditionally is considered

some kind of purging substance,

like having a medicine

that cleans you up.

- And then you have a

series of hallucinations

that are very much a kind

of religious experience,

almost a kind of psychosis.

- [Narrator] It's a

psychosis best explained

by the number 13.

Ayahuasca's powerful

effects can be attributed

to its main active ingredient

dimethyltryptamine or DMT,

a chemical in the brain

associated with near

death experiences.

- People often describe

leaving the experience

as a feeling reborn.

And so to be reborn,

one must die in a

spiritual sense.

And this is a common

description that we see

even in people recently

who've tried Ayahuasca.

- Because end of the day,

we're talking about the

great mysteries of life,

and we still have a lot

of existential questions.

- [Narrator] In a

recent scientific study,

out of 13 volunteers, given DMT,

all 13 have out of

body experiences.

- [Comical voice] Hey,

has anyone seen my body?

- [Narrator] Sixty six

percent report meeting aliens,

robots were elves

during their trip.

- [Comical voice] Oh,

not the probe, again.

- [Narrator] And 80%

reported their experiences

under the influence are more

real than their waking lives.

- Whether you're talking

about the Siberian shaman,

who traveled through the trees

and go up into the spirit world,

or whether you're talking

about the Peruvian shamans

who do the same with the

vine of the soul, Ayahuasca

there is the sense of traveling

through some sort

of spirit world

that cuts across psychedelic

rituals across the planet.

- [Narrator] But indigenous

peoples are not the only ones

who've had their culture

shaped by psychedelics.

It turns out, so was the west.

If you've ever counted how

many days till Christmas,

you've been waiting for

one of the patron saints

of psychedelia.

- There is speculation

that Santa Claus

was a mushroom,

Amanita muscaria,

because it is a red and

white buttoned mushrooms.

- He goes on a trip across

the sky with flying reindeer,

a species that also incidentally

loves to eat mushrooms,

especially Amanita

muscaria mushrooms.

- A dude's going to

come into your home

and not steal your things,

but he'll give you

things, you know,

like, all he asks is milk.

- You have all sorts of

characters dealing drugs.

You got Santa Claus,

apparently, leprechauns,

my old college roommates.

- [Narrator] But Santa

isn't the only trace

of psychedelics in

Western culture.

One of the active ingredients

in LSD is nothing new.

It's called, Ergot,

a fungal parasite

that develops on crops, such

as oats, rye, barley, and rice.

Hoffman thought he was the first

to go on the trip of a lifetime.

It turns out he was more

like the 6 millionth.

Let's rewind 2,500

years to ancient Greece.

Socrates, yes, that Socrates,

was one of 6 million men were

inducted into a secret society

known as the

Eleusinian mysteries,

a multi-day ritual with

a psychedelic conclusion.

- We know that people were

pilgrimaging for multiple days,

praying, chanting in

these large groups

and at the very

end taking a drink

that cause them to

have experiences

that were incredible,

but we don't know what

exactly the elixir they take

at the end to hallucinate, was.

- [Narrator] This

elixir was called Kykeon

and no one knows what the

active ingredient was,

but psychedelic scholar,

Gordon Wasson, remember him?

He had a theory.

- He suggested that wasn't

in fact psychoactive

and that it was based on ergot,

which of course years

later, Albert Hoffman,

would be working with

when he discovered LSD.

- [Narrator] Ancient

Greece was not the first

or last culture in the

west to tangle with ergot,

which has proved to

be both a blessing

and a curse to humanity.

- Remember the

adage of Paracelsus,

the difference from

a poison, a drug,

and hallucinogen and

narcotic, is just dosage.

- [Narrator] In the middle ages,

ergot was both a

poison and a drug.

Midwives used it

to aid childbirth,

but a tainted loaf of rye bread

could cause temporary

madness or worse.

- Ergot, this curious

fungal parasite

that caused St Anthony's fire

when entire medieval towns

would go crazy and

fingers would go necrotic

and noses would fall off.

- Lots of people in medieval

Europe and in the Americas

understood not to eat ergot,

and to remove it from the rye.

But sometimes people didn't know

and it can decimate a village.

- what is a hallucinogen?

What is a poison?

I mean the key thing is

whether or not a culture

is able to use a plant

substance in helpful ways.

- [Narrator] How can you

tell the difference between

psychedelic good

and psychedelic bad?

In 17th century, New England,

the number 24 will show

just how bad it can get.

It's 1692, a nine-year-old Betty

Parris is not feeling well.

After she and her friends

dabble in fortune telling,

she develops a fever.

But soon she is hiding

under furniture.

(Evil laughing)

Then she barks like a dog.

(dark barking and howling)

She has uncontrollable

screaming fits,

and then the condition

spreads to her friends.

(Kids screaming)

- We're talking about

a very restricted

conservative society.

Any sort of strange behavior,

especially on the

part of young girls

would have been

viewed as heresy.

- [Narrator] The local minister

believes she's bewitched

and it will end badly in

the Salem witch trials.

(child screaming)

- I remember watching

Salem witch trial movies

when I was in

junior high school.

And it was just put forward

that these witches

had gone crazy.

More recently,

there is speculation

that they might have been

eating tainted bread with ergot.

- What she was experiencing

may have been in her mind,

or it may have been LSD.

We have many examples

in the past of ergotism

impacting entire communities.

And even fairly

recently in the 1950s

that occurred in France

And in 2001 in Ethiopia,

this is not something

relegated to the past.

- [Narrator] During

the Salem witch trials,

over 200 people are

accused of witchcraft.

Thirty are found guilty.

Nineteen are hanged.

Four die in prison.

And one is crushed to

death under stones.

That's a total of 24 deaths

and countless ruined lives.

Betty Parris was lucky.

She survived the witch hunts.

But 300 years later,

a new kind of witch

hunt is taking place.

Remember Woodstock in

the summer of 1969?

Well, 400,000 party-goers

are about to come up against

the power of the number one.

- LSD and the hope for society

based on benevolent

shared consciousness

is bumping up against

the reality of our crimes

in the Vietnam w*r

and the race riots

and the racial

tension here at home.

And it becomes clear that

LSD can't fix that stuff.

What's more, LSD starts to

look like a source of crime.

- [Narrator] At the

same time as Woodstock,

a gruesome mass m*rder in

Hollywood shocks America.

These seven murders

were committed by a

g*ng of hippie th*gs

known as the Manson family.

Charles Manson is

said to have used LSD

to control his followers

and reshape their sense

of morality and reality.

- When it came to

the Manson trial,

that was everything

the government needed.

People take this, they

commit acts like this,

and that was extremely

powerful anti LSD advertisement

right there.

- There was a lot of hysteria

about people painting LSD

on door knobs or putting

it in Halloween candy.

There was never any documented

evidence of this occurring,

but this really scares

a lot of Americans.

- [Narrator] LSD has

already been classified

as a schedule 1

controlled substance,

the same legal

category as heroin.

- I am glad that in

this administration,

we have increased

the amount of money for

handling the problem

of dangerous drugs, seven fold.

- [Narrator] In 1971, President

Richard Nixon goes further

and declares drugs to be

public enemy number one,

putting psychedelics

squarely in U S law

enforcement's crosshairs.

Then in the 1980s,

Nancy Reagan spearheads

the w*r on drugs with her,

Just say no, campaign.

- It's never been because

the drug is bad for you.

It's always been a way to

target the community using it.

You have marijuana

in the early 1900s,

which target Mexican laborers.

Then you have the

criminalization of cocaine,

which was targeting the

African-American community.

- Prohibition is about

a hundred years old

and it's a kind of anomaly

in the history of humankind

if you look in the

bigger picture.

- The w*r on drugs has

gone on now for 50 years,

it's cost a trillion dollars.

A trillion dollars is

a stack of dollar bills

that would reach a quarter

of the way to the moon.

And today, there are more

people in more places

using worst drugs in worse

ways than ever before.

- [Narrator] The

number of Americans

arrested for drug possession

has tripled since 1980.

Every 25 seconds,

somebody is arrested

for drug possession in the U S.

In 2015, there are

1.3 million arrests.

That's the equivalent of

one in every 252 Americans,

Twenty percent of the

prison population,

or 456,000 individuals are

serving time on a drug charge.

That costs the Federal

Government $9.2

million every day

or 3.3 billion annually.

- w*r on drugs, that's

just not gonna work.

- It feels like a failure, yeah.

- To be honest with you,

I think there's other

bigger battles to fight,

w*r on poverty, how about that?

- [Narrator] ill*gal or not,

new drugs keep

coming into fashion.

In the 1990s, a

whole new generation

experiences their

version of psychedelia.

So how many letters

does love have?

The answer turns out to be 29.

Methylenedioxy methamphetamine

is a 29 letter word

that shortened to MDMA.

And as otherwise

known as ecstasy.

- MDMA both encourages

the release of serotonin,

but also inhibit the

uptake of serotonin.

So people get really flooded

by this feel-good

neurotransmitter.

It makes them want to

dance and hug,

and it's like receiving

the best news of your life

when nothing really

has happened.

- [Narrator] Known

as the love drug,

It is the fuel for rave and

electronic dance music culture

that starts in the eighties

and is only getting bigger.

It's not hard to see

the allure of a pill

that promises ecstasy.

But MDMAs blast of bliss

can put users in

dangerous situations.

A handful of MDMA

deaths by dehydration,

set off a moral panic in

Britain, in the 1980s.

- There were some

deaths because of it.

What happened in the 1980s,

especially in the UK,

was that MDMA was used

at very early raves.

And some of these clubs

were turning off the taps

in the bathroom and then selling

cups of tap water for $15.

There was no ventilation

in the dance clubs.

They were overheating

on the MDMA

and they weren't realizing it

because they were having

such a serotonin-based

blissful experience.

- [Narrator] More recently,

the psychedelic spotlight

has returned to California.

This time it's not naked

hippies or groovy Hells Angels.

It's the digital denisons

of Silicon Valley

who are hacking the

technology of their own bodies

by microdosing.

Remember Albert Hofmann

and what 250

micrograms did to him?

Well, what if you took

something smaller, much smaller,

say 10 micrograms,

what would happen then?

- Microdosing is taking

very small amounts of LSD

that will not produce the

kinds of hallucinations

that a larger dose

would produce.

But might produce a mood shift.

- People are taking

very minute doses

much less than you

would take to get high

and using that instead of

mood stabilizing drugs.

And considering how many bad

side effects are associated

with the current pharmacology

around treating

depression, anxiety,

this may be a really

great solution.

- Microdosing is like

a sneaky, fancy way

to use drugs at work.

But like if you

work at a startup,

I feel like the company

just gives you some

on your first day.

- If it actually

helps people, great.

So, yeah, I think

it's worthy of study.

- [Narrator] After decades

when it was impossible

to study psychedelics legally,

therefore is to

follow the same path

that cannabis took

to legalization.

First medical then recreational.

And now billions of

dollars of investment

is pouring into the

psychedelic startup sector.

In the last two decades,

the number of people

using LSD in the U S

has increased by over 200%.

And you're more

likely to be a user

if you have a college degree,

are single, divorced

or separated,

and you're in your late

thirties or forties.

The middle class is the

new psychedelic generation,

sorry hippies.

In the USA, 17

states have legalized

the recreational

use of cannabis,

36 have legalized it's use

for medicinal purposes.

One state has taken

this a step further

into the realm of

the psychedelics.

- Just this last year,

Oregon voted to

openly allow the sale

and distribution of

psilocybin mushrooms.

I hope to see for the

future of psychedelics,

that there's more openness

to researching their

possible uses in humans.

- On the positive side,

I see psychiatry embracing

psychedelic therapy,

but the money behind it

is going to drive false

claims about psychedelics.

And you're going to

see more and more

that the medical industry is

going to push psychedelics

into places where they

might not necessarily fit.

- I do think certain

psychedelics will become legal,

especially for medical reasons,

but it is still ill*gal.

I do not promote it.

I do not encourage

anybody to do it.

- Without dough, substance

like ecstasy is ideal

for couples therapy.

It's ideal

for post-traumatic stress.

A substance like the

tryptamines mushrooms,

I can see being extremely

valuable for palliative care,

for hospice care, for

end of life counseling.

- I think it's important

to really understand

that psychedelics is not

a panache for everything,

not a magic solution.

And it's not for everybody.

- Hey, kids don't do drugs,

but if you do do drugs,

picture you'd have snacks.

- Oh God, my parents are

gonna watch this and be like,

oh my God, my son

is a drug addict.

They need to do shrooms.

- I've had some ideas

that I've written down

when I was on psychedelics

and they weren't so good.

- That's why I

don't tend to mess

with those kinds of things

'cause I'm like, a

small amount of that

can do irreparable damage.

I just want to know that

I can do basic arithmetic

when I come back.

(upbeat music)